BDBM50214988 CHEMBL393873::trans-N-(2-(5-chloro-1H-indole-2-carboxamido)cyclopentyl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide

SMILES: CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=LFQOOGATGPTOMY-HZPDHXFCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50214988   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50214988 (CHEMBL393873 | trans-N-(2-(5-chloro-1H-indole-2-ca...) Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C22H24ClN5O2S/c1-28-8-7-17-19(11-28)31-22(27-17)21(30)26-16-4-2-3-15(16)25-20(29)18-10-12-9-13(23)5-6-14(12)24-18/h5-6,9-10,15-16,24H,2-4,7-8,11H2,1H3,(H,25,29)(H,26,30)/t15-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human factor 10a after 10 seconds				Bioorg Med Chem Lett 17: 4683-8 (2007) Article DOI: 10.1016/j.bmcl.2007.05.068 BindingDB Entry DOI: 10.7270/Q2183660
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50214988 (CHEMBL393873 | trans-N-(2-(5-chloro-1H-indole-2-ca...) Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C22H24ClN5O2S/c1-28-8-7-17-19(11-28)31-22(27-17)21(30)26-16-4-2-3-15(16)25-20(29)18-10-12-9-13(23)5-6-14(12)24-18/h5-6,9-10,15-16,24H,2-4,7-8,11H2,1H3,(H,25,29)(H,26,30)/t15-,16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human factor 2a after 10 seconds				Bioorg Med Chem Lett 17: 4683-8 (2007) Article DOI: 10.1016/j.bmcl.2007.05.068 BindingDB Entry DOI: 10.7270/Q2183660
					More data for this Ligand-Target Pair