null

SMILES: Cc1cn(Cc2ccc3OCOc3c2)c2cc(ccc12)C(=O)Nc1c(Cl)c[n+]([O-])cc1Cl

InChI Key: InChIKey=UHUZDJMHKDQSSG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50215108 (CHEMBL102758) Show SMILES Cc1cn(Cc2ccc3OCOc3c2)c2cc(ccc12)C(=O)Nc1c(Cl)c[n+]([O-])cc1Cl Show InChI InChI=1S/C23H17Cl2N3O4/c1-13-8-27(9-14-2-5-20-21(6-14)32-12-31-20)19-7-15(3-4-16(13)19)23(29)26-22-17(24)10-28(30)11-18(22)25/h2-8,10-11H,9,12H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)				Bioorg Med Chem Lett 8: 3053-8 (1998) BindingDB Entry DOI: 10.7270/Q2PV6NK6
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50215108 (CHEMBL102758) Show SMILES Cc1cn(Cc2ccc3OCOc3c2)c2cc(ccc12)C(=O)Nc1c(Cl)c[n+]([O-])cc1Cl Show InChI InChI=1S/C23H17Cl2N3O4/c1-13-8-27(9-14-2-5-20-21(6-14)32-12-31-20)19-7-15(3-4-16(13)19)23(29)26-22-17(24)10-28(30)11-18(22)25/h2-8,10-11H,9,12H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase type IV (PDE4) activity				Bioorg Med Chem Lett 8: 3053-8 (1998) BindingDB Entry DOI: 10.7270/Q2PV6NK6
					More data for this Ligand-Target Pair