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SMILES: CN(CCc1ccccn1)CCn1c(=O)c2CN(Cc3ccc(cc3)C(C)(C)C)CCc2n(Cc2c(F)cccc2F)c1=O

InChI Key: InChIKey=IEKFIZICLFDORP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215216   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50215216
PNG
(1-(2,6-difluorobenzyl)-6-(4-tert-butylbenzyl)-3-(2...)
Show SMILES CN(CCc1ccccn1)CCn1c(=O)c2CN(Cc3ccc(cc3)C(C)(C)C)CCc2n(Cc2c(F)cccc2F)c1=O
Show InChI InChI=1S/C35H41F2N5O2/c1-35(2,3)26-13-11-25(12-14-26)22-40-19-16-32-29(23-40)33(43)41(21-20-39(4)18-15-27-8-5-6-17-38-27)34(44)42(32)24-28-30(36)9-7-10-31(28)37/h5-14,17H,15-16,18-24H2,1-4H3
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Similars
Article
PubMed
 300n/an/an/an/an/an/an/an/a



Neurocrine Biosciences

Curated by ChEMBL


Assay Description
Displacement of [125I-His5,D-Tyr6]GnRH from human cloned GnRH receptor transfected in COS7 cells

Bioorg Med Chem 15: 5590-603 (2007)


Article DOI: 10.1016/j.bmc.2007.05.029
BindingDB Entry DOI: 10.7270/Q2VH5NJG
More data for this
Ligand-Target Pair