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SMILES: CN(CCc1ccccn1)CCn1c(=O)c2CN(Cc3ccccc3C)CCc2n(Cc2c(F)cccc2F)c1=O

InChI Key: InChIKey=PDQCJZJFEPQKRT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215217   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50215217
PNG
(1-(2,6-difluoro-benzyl)-6-(2-methyl-benzyl)-3-{2-[...)
Show SMILES CN(CCc1ccccn1)CCn1c(=O)c2CN(Cc3ccccc3C)CCc2n(Cc2c(F)cccc2F)c1=O
Show InChI InChI=1S/C32H35F2N5O2/c1-23-8-3-4-9-24(23)20-37-17-14-30-27(21-37)31(40)38(19-18-36(2)16-13-25-10-5-6-15-35-25)32(41)39(30)22-26-28(33)11-7-12-29(26)34/h3-12,15H,13-14,16-22H2,1-2H3
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Similars
Article
PubMed
 85n/an/an/an/an/an/an/an/a



Neurocrine Biosciences

Curated by ChEMBL


Assay Description
Displacement of [125I-His5,D-Tyr6]GnRH from human cloned GnRH receptor transfected in COS7 cells

Bioorg Med Chem 15: 5590-603 (2007)


Article DOI: 10.1016/j.bmc.2007.05.029
BindingDB Entry DOI: 10.7270/Q2VH5NJG
More data for this
Ligand-Target Pair