BindingDB logo
myBDB logout

null

SMILES: Fc1cccc(F)c1Cn1c2CCN(Cc3ccc(Cl)cc3)Cc2c(=O)n(C[C@H]2CCCN2Cc2ccccn2)c1=O

InChI Key: InChIKey=ZYFQUKXLKFLJCB-RUZDIDTESA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215218   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50215218
PNG
((R)-1-(2,6-difluorobenzyl)-6-(4-chlorobenzyl)-3-((...)
Show SMILES Fc1cccc(F)c1Cn1c2CCN(Cc3ccc(Cl)cc3)Cc2c(=O)n(C[C@H]2CCCN2Cc2ccccn2)c1=O
Show InChI InChI=1S/C32H32ClF2N5O2/c33-23-11-9-22(10-12-23)17-37-16-13-30-27(20-37)31(41)40(32(42)39(30)21-26-28(34)7-3-8-29(26)35)19-25-6-4-15-38(25)18-24-5-1-2-14-36-24/h1-3,5,7-12,14,25H,4,6,13,15-21H2/t25-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 20n/an/an/an/an/an/an/an/a



Neurocrine Biosciences

Curated by ChEMBL


Assay Description
Displacement of [125I-His5,D-Tyr6]GnRH from human cloned GnRH receptor transfected in COS7 cells

Bioorg Med Chem 15: 5590-603 (2007)


Article DOI: 10.1016/j.bmc.2007.05.029
BindingDB Entry DOI: 10.7270/Q2VH5NJG
More data for this
Ligand-Target Pair