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BDBM50215309 CHEMBL102193

SMILES: Cc1ccc(NS(=O)(=O)c2ccc3OCCc3c2)c(=O)n1CC(=O)NCc1ccc2[nH]nc(N)c2c1

InChI Key: InChIKey=VDXAXVGFABNSET-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215309   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50215309
PNG
(CHEMBL102193)
Show SMILES Cc1ccc(NS(=O)(=O)c2ccc3OCCc3c2)c(=O)n1CC(=O)NCc1ccc2[nH]nc(N)c2c1
Show InChI InChI=1S/C24H24N6O5S/c1-14-2-5-20(29-36(33,34)17-4-7-21-16(11-17)8-9-35-21)24(32)30(14)13-22(31)26-12-15-3-6-19-18(10-15)23(25)28-27-19/h2-7,10-11,29H,8-9,12-13H2,1H3,(H,26,31)(H3,25,27,28)
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PubMed
 29n/an/an/an/an/an/an/an/a



Corvas International, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrate

Bioorg Med Chem Lett 12: 2925-30 (2002)


BindingDB Entry DOI: 10.7270/Q27946WJ
More data for this
Ligand-Target Pair