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BDBM50215313 CHEMBL101669

SMILES: Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc2[nH]nc(O)c2c1

InChI Key: InChIKey=IMZQOJBVWCOHFL-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215313   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50215313
PNG
(CHEMBL101669)
Show SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc2[nH]nc(O)c2c1
Show InChI InChI=1S/C23H24N6O3/c1-15-12-26-21(24-10-9-16-5-3-2-4-6-16)23(32)29(15)14-20(30)25-13-17-7-8-19-18(11-17)22(31)28-27-19/h2-8,11-12H,9-10,13-14H2,1H3,(H,24,26)(H,25,30)(H2,27,28,31)
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PubMed
 33n/an/an/an/an/an/an/an/a



Corvas International, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrate

Bioorg Med Chem Lett 12: 2925-30 (2002)


BindingDB Entry DOI: 10.7270/Q27946WJ
More data for this
Ligand-Target Pair