BDBM50215399 CHEMBL174575

SMILES: CCCC(CCC)(CC(=O)Nc1cccc(OCc2ccc3ccc(F)cc3n2)c1)C(O)=O

InChI Key: InChIKey=FKGPTFPCZZCYKN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215399   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50215399 (CHEMBL174575) Show SMILES CCCC(CCC)(CC(=O)Nc1cccc(OCc2ccc3ccc(F)cc3n2)c1)C(O)=O Show InChI InChI=1S/C26H29FN2O4/c1-3-12-26(13-4-2,25(31)32)16-24(30)29-20-6-5-7-22(15-20)33-17-21-11-9-18-8-10-19(27)14-23(18)28-21/h5-11,14-15H,3-4,12-13,16-17H2,1-2H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro for antagonistic activity against LTD4 receptor in guinea pig ileum				Bioorg Med Chem Lett 8: 965-70 (1999) BindingDB Entry DOI: 10.7270/Q2V123XT
					More data for this Ligand-Target Pair