BDBM50215502 6-methoxy-4-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL248110

SMILES: COc1ccc2[nH]c3C(NCC(C)c3c2c1)C(O)=O

InChI Key: InChIKey=IGCZCYUOHYYYTG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215502 (6-methoxy-4-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,...) Show SMILES COc1ccc2[nH]c3C(NCC(C)c3c2c1)C(O)=O |w:8.18,11.11| Show InChI InChI=1S/C14H16N2O3/c1-7-6-15-13(14(17)18)12-11(7)9-5-8(19-2)3-4-10(9)16-12/h3-5,7,13,15-16H,6H2,1-2H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair