BDBM50215525 7-hydroxy-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL247343

SMILES: COc1cc2c3CCNC(C(O)=O)c3[nH]c2cc1O

InChI Key: InChIKey=IYQLUTFBWWAEID-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215525 (7-hydroxy-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3...) Show SMILES COc1cc2c3CCNC(C(O)=O)c3[nH]c2cc1O |w:9.9| Show InChI InChI=1S/C13H14N2O4/c1-19-10-4-7-6-2-3-14-12(13(17)18)11(6)15-8(7)5-9(10)16/h4-5,12,14-16H,2-3H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair