BDBM50215526 6-methoxy-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL396151

SMILES: COc1ccc2[nH]c3c(CCNC3(C)C(O)=O)c2c1

InChI Key: InChIKey=BETCVGLWCYMGME-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50215526 (6-methoxy-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,...) Show SMILES COc1ccc2[nH]c3c(CCNC3(C)C(O)=O)c2c1 |w:12.13| Show InChI InChI=1S/C14H16N2O3/c1-14(13(17)18)12-9(5-6-15-14)10-7-8(19-2)3-4-11(10)16-12/h3-4,7,15-16H,5-6H2,1-2H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MK2				Bioorg Med Chem Lett 17: 4657-63 (2007) Article DOI: 10.1016/j.bmcl.2007.05.070 BindingDB Entry DOI: 10.7270/Q2PR7VPC
					More data for this Ligand-Target Pair