BDBM50215554 2-(fluoromethyl)4-(2-(3-methoxyphenyl)ethynyl)thiazole::CHEMBL229911

SMILES: COc1cccc(c1)C#Cc1csc(CF)n1

InChI Key: InChIKey=ACGWDWBCEMCJBH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50215554 (2-(fluoromethyl)4-(2-(3-methoxyphenyl)ethynyl)thia...) Show SMILES COc1cccc(c1)C#Cc1csc(CF)n1 Show InChI InChI=1S/C13H10FNOS/c1-16-12-4-2-3-10(7-12)5-6-11-9-17-13(8-14)15-11/h2-4,7,9H,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat brain membrane				J Med Chem 50: 3256-66 (2007) Article DOI: 10.1021/jm0701268 BindingDB Entry DOI: 10.7270/Q2FB52NB
					More data for this Ligand-Target Pair