BDBM50215641 3-(3-chloro-4-fluorophenyl)-1-((3R,6S)-6-(3-cyanophenyl)bicyclo[4.1.0]heptan-3-yl)-1-((1-(methylsulfonyl)piperidin-4-yl)methyl)urea::CHEMBL229871

SMILES: CS(=O)(=O)N1CCC(CN([C@@H]2CC[C@@]3(CC3C2)c2cccc(c2)C#N)C(=O)Nc2ccc(F)c(Cl)c2)CC1

InChI Key: InChIKey=WRWSEAQZUQAVSE-FKCQOYNMSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50215641 (3-(3-chloro-4-fluorophenyl)-1-((3R,6S)-6-(3-cyanop...) Show SMILES CS(=O)(=O)N1CCC(CN([C@@H]2CC[C@@]3(CC3C2)c2cccc(c2)C#N)C(=O)Nc2ccc(F)c(Cl)c2)CC1 |w:15.16| Show InChI InChI=1S/C28H32ClFN4O3S/c1-38(36,37)33-11-8-19(9-12-33)18-34(27(35)32-23-5-6-26(30)25(29)15-23)24-7-10-28(16-22(28)14-24)21-4-2-3-20(13-21)17-31/h2-6,13,15,19,22,24H,7-12,14,16,18H2,1H3,(H,32,35)/t22?,24-,28-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Cartagena Curated by ChEMBL					Assay Description Antagonist activity at MCH1 receptor				Eur J Med Chem 45: 4509-22 (2010) Article DOI: 10.1016/j.ejmech.2010.07.011 BindingDB Entry DOI: 10.7270/Q2FT8N9V
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50215641 (3-(3-chloro-4-fluorophenyl)-1-((3R,6S)-6-(3-cyanop...) Show SMILES CS(=O)(=O)N1CCC(CN([C@@H]2CC[C@@]3(CC3C2)c2cccc(c2)C#N)C(=O)Nc2ccc(F)c(Cl)c2)CC1 |w:15.16| Show InChI InChI=1S/C28H32ClFN4O3S/c1-38(36,37)33-11-8-19(9-12-33)18-34(27(35)32-23-5-6-26(30)25(29)15-23)24-7-10-28(16-22(28)14-24)21-4-2-3-20(13-21)17-31/h2-6,13,15,19,22,24H,7-12,14,16,18H2,1H3,(H,32,35)/t22?,24-,28-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in CHO cells				Bioorg Med Chem 15: 5369-85 (2007) Article DOI: 10.1016/j.bmc.2007.05.068 BindingDB Entry DOI: 10.7270/Q25T3K5V
					More data for this Ligand-Target Pair