null

SMILES: CC(C)N(CCN([C@@H]1CC[C@@]2(CC2C1)c1cccc(Br)c1)C(=O)Nc1ccc(F)c(F)c1)C(C)C

InChI Key: InChIKey=AVQPXABTEFSDRR-UOOTYMSZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50215651 (1-((3R,6S)-6-(3-bromophenyl)bicyclo[4.1.0]heptan-3...) Show SMILES CC(C)N(CCN([C@@H]1CC[C@@]2(CC2C1)c1cccc(Br)c1)C(=O)Nc1ccc(F)c(F)c1)C(C)C |w:12.13| Show InChI InChI=1S/C28H36BrF2N3O/c1-18(2)33(19(3)4)12-13-34(27(35)32-23-8-9-25(30)26(31)16-23)24-10-11-28(17-21(28)15-24)20-6-5-7-22(29)14-20/h5-9,14,16,18-19,21,24H,10-13,15,17H2,1-4H3,(H,32,35)/t21?,24-,28-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Cartagena Curated by ChEMBL					Assay Description Antagonist activity at MCH1 receptor				Eur J Med Chem 45: 4509-22 (2010) Article DOI: 10.1016/j.ejmech.2010.07.011 BindingDB Entry DOI: 10.7270/Q2FT8N9V
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50215651 (1-((3R,6S)-6-(3-bromophenyl)bicyclo[4.1.0]heptan-3...) Show SMILES CC(C)N(CCN([C@@H]1CC[C@@]2(CC2C1)c1cccc(Br)c1)C(=O)Nc1ccc(F)c(F)c1)C(C)C |w:12.13| Show InChI InChI=1S/C28H36BrF2N3O/c1-18(2)33(19(3)4)12-13-34(27(35)32-23-8-9-25(30)26(31)16-23)24-10-11-28(17-21(28)15-24)20-6-5-7-22(29)14-20/h5-9,14,16,18-19,21,24H,10-13,15,17H2,1-4H3,(H,32,35)/t21?,24-,28-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in CHO cells				Bioorg Med Chem 15: 5369-85 (2007) Article DOI: 10.1016/j.bmc.2007.05.068 BindingDB Entry DOI: 10.7270/Q25T3K5V
					More data for this Ligand-Target Pair