BDBM50215737 CHEMBL50425
SMILES: O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O
InChI Key: InChIKey=MYBPPTDUKUIWHM-RBISFHTESA-N
Data: 8 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50215737 (CHEMBL50425) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole blood | Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50215737 (CHEMBL50425) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole blood | Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50215737 (CHEMBL50425) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils | Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50215737 (CHEMBL50425) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. | Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50215737 (CHEMBL50425) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. | Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50215737 (CHEMBL50425) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. | Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50215737 (CHEMBL50425) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. | Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50215737 (CHEMBL50425) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils | Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1 | |||||||||||
More data for this Ligand-Target Pair |