BDBM50215751 2-(4-(2-(pyridin-3-yl)vinyl)-1H-pyrazol-3-yl)-1H-imidazole-4-carbonitrile::CHEMBL394466

SMILES: N#Cc1cnc([nH]1)-c1n[nH]cc1C=Cc1cccnc1

InChI Key: InChIKey=QJUNJGLRELVJKL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215751   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50215751 (2-(4-(2-(pyridin-3-yl)vinyl)-1H-pyrazol-3-yl)-1H-i...) Show SMILES N#Cc1cnc([nH]1)-c1n[nH]cc1C=Cc1cccnc1 |w:13.15| Show InChI InChI=1S/C14H10N6/c15-6-12-9-17-14(19-12)13-11(8-18-20-13)4-3-10-2-1-5-16-7-10/h1-5,7-9H,(H,17,19)(H,18,20)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Inhibition of HER2				Bioorg Med Chem Lett 17: 4557-61 (2007) Article DOI: 10.1016/j.bmcl.2007.05.092 BindingDB Entry DOI: 10.7270/Q2DB81JD
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50215751 (2-(4-(2-(pyridin-3-yl)vinyl)-1H-pyrazol-3-yl)-1H-i...) Show SMILES N#Cc1cnc([nH]1)-c1n[nH]cc1C=Cc1cccnc1 |w:13.15| Show InChI InChI=1S/C14H10N6/c15-6-12-9-17-14(19-12)13-11(8-18-20-13)4-3-10-2-1-5-16-7-10/h1-5,7-9H,(H,17,19)(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Inhibition of aurora-A				Bioorg Med Chem Lett 17: 4557-61 (2007) Article DOI: 10.1016/j.bmcl.2007.05.092 BindingDB Entry DOI: 10.7270/Q2DB81JD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50215751 (2-(4-(2-(pyridin-3-yl)vinyl)-1H-pyrazol-3-yl)-1H-i...) Show SMILES N#Cc1cnc([nH]1)-c1n[nH]cc1C=Cc1cccnc1 |w:13.15| Show InChI InChI=1S/C14H10N6/c15-6-12-9-17-14(19-12)13-11(8-18-20-13)4-3-10-2-1-5-16-7-10/h1-5,7-9H,(H,17,19)(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 17: 4557-61 (2007) Article DOI: 10.1016/j.bmcl.2007.05.092 BindingDB Entry DOI: 10.7270/Q2DB81JD
					More data for this Ligand-Target Pair