BDBM50215790 2-((2-(3-(1H-imidazol-1-yl)propylamino)pyridin-4-yl)methylamino)-N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)benzamide::CHEMBL247424

SMILES: FC1(F)Oc2ccc(NC(=O)c3ccccc3NCc3ccnc(NCCCn4ccnc4)c3)cc2O1

InChI Key: InChIKey=NRCYJQOXMJLQTP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50215790 (2-((2-(3-(1H-imidazol-1-yl)propylamino)pyridin-4-y...) Show SMILES FC1(F)Oc2ccc(NC(=O)c3ccccc3NCc3ccnc(NCCCn4ccnc4)c3)cc2O1 Show InChI InChI=1S/C26H24F2N6O3/c27-26(28)36-22-7-6-19(15-23(22)37-26)33-25(35)20-4-1-2-5-21(20)32-16-18-8-10-31-24(14-18)30-9-3-12-34-13-11-29-17-34/h1-2,4-8,10-11,13-15,17,32H,3,9,12,16H2,(H,30,31)(H,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant cKit by FRET assay				Bioorg Med Chem Lett 17: 4378-81 (2007) Article DOI: 10.1016/j.bmcl.2007.02.075 BindingDB Entry DOI: 10.7270/Q28K78S7
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50215790 (2-((2-(3-(1H-imidazol-1-yl)propylamino)pyridin-4-y...) Show SMILES FC1(F)Oc2ccc(NC(=O)c3ccccc3NCc3ccnc(NCCCn4ccnc4)c3)cc2O1 Show InChI InChI=1S/C26H24F2N6O3/c27-26(28)36-22-7-6-19(15-23(22)37-26)33-25(35)20-4-1-2-5-21(20)32-16-18-8-10-31-24(14-18)30-9-3-12-34-13-11-29-17-34/h1-2,4-8,10-11,13-15,17,32H,3,9,12,16H2,(H,30,31)(H,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of b-Raf				Bioorg Med Chem Lett 17: 4378-81 (2007) Article DOI: 10.1016/j.bmcl.2007.02.075 BindingDB Entry DOI: 10.7270/Q28K78S7
					More data for this Ligand-Target Pair