BDBM50215799 2-((2-(2-(1H-imidazol-5-yl)ethylamino)pyridin-4-yl)methylamino)-N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)benzamide::CHEMBL247792

SMILES: FC1(F)Oc2ccc(NC(=O)c3ccccc3NCc3ccnc(NCCc4cnc[nH]4)c3)cc2O1

InChI Key: InChIKey=FLYZOVOQWUDRBN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215799   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50215799 (2-((2-(2-(1H-imidazol-5-yl)ethylamino)pyridin-4-yl...) Show SMILES FC1(F)Oc2ccc(NC(=O)c3ccccc3NCc3ccnc(NCCc4cnc[nH]4)c3)cc2O1 Show InChI InChI=1S/C25H22F2N6O3/c26-25(27)35-21-6-5-17(12-22(21)36-25)33-24(34)19-3-1-2-4-20(19)31-13-16-7-9-29-23(11-16)30-10-8-18-14-28-15-32-18/h1-7,9,11-12,14-15,31H,8,10,13H2,(H,28,32)(H,29,30)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant cKit by FRET assay				Bioorg Med Chem Lett 17: 4378-81 (2007) Article DOI: 10.1016/j.bmcl.2007.02.075 BindingDB Entry DOI: 10.7270/Q28K78S7
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50215799 (2-((2-(2-(1H-imidazol-5-yl)ethylamino)pyridin-4-yl...) Show SMILES FC1(F)Oc2ccc(NC(=O)c3ccccc3NCc3ccnc(NCCc4cnc[nH]4)c3)cc2O1 Show InChI InChI=1S/C25H22F2N6O3/c26-25(27)35-21-6-5-17(12-22(21)36-25)33-24(34)19-3-1-2-4-20(19)31-13-16-7-9-29-23(11-16)30-10-8-18-14-28-15-32-18/h1-7,9,11-12,14-15,31H,8,10,13H2,(H,28,32)(H,29,30)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of b-Raf				Bioorg Med Chem Lett 17: 4378-81 (2007) Article DOI: 10.1016/j.bmcl.2007.02.075 BindingDB Entry DOI: 10.7270/Q28K78S7
					More data for this Ligand-Target Pair