BDBM50215816 2-(4-acetylphenylamino)-N,N-diisopentyl-3-(3-(piperidin-1-yl)propyl)-3H-benzo[d]imidazole-5-carboxamide::CHEMBL233135
SMILES: CC(C)CCN(CCC(C)C)C(=O)c1ccc2nc(Nc3ccc(cc3)C(C)=O)n(CCCN3CCCCC3)c2c1
InChI Key: InChIKey=CXGYZUHRSDOJIS-UHFFFAOYSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50215816 (2-(4-acetylphenylamino)-N,N-diisopentyl-3-(3-(pipe...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Displacement of [125I]NDP-alphaMSH from human melanocortin 4 receptor expressed in CHOK1 cells | Bioorg Med Chem Lett 17: 4464-70 (2007) Article DOI: 10.1016/j.bmcl.2007.06.010 BindingDB Entry DOI: 10.7270/Q24T6J2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50215816 (2-(4-acetylphenylamino)-N,N-diisopentyl-3-(3-(pipe...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Displacement of [125I]NDP-alphaMSH from human melanocortin 4 receptor expressed in CHOK1 cells | Bioorg Med Chem Lett 17: 4464-70 (2007) Article DOI: 10.1016/j.bmcl.2007.06.010 BindingDB Entry DOI: 10.7270/Q24T6J2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 3 (Homo sapiens (Human)) | BDBM50215816 (2-(4-acetylphenylamino)-N,N-diisopentyl-3-(3-(pipe...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Displacement of [125I]NDP-alphaMSH from human melanocortin 3 receptor expressed in CHOK1 cells | Bioorg Med Chem Lett 17: 4464-70 (2007) Article DOI: 10.1016/j.bmcl.2007.06.010 BindingDB Entry DOI: 10.7270/Q24T6J2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 5 (MC5R) (Homo sapiens (Human)) | BDBM50215816 (2-(4-acetylphenylamino)-N,N-diisopentyl-3-(3-(pipe...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Displacement of [125I]NDP-alphaMSH from human melanocortin 5 receptor expressed in CHOK1 cells | Bioorg Med Chem Lett 17: 4464-70 (2007) Article DOI: 10.1016/j.bmcl.2007.06.010 BindingDB Entry DOI: 10.7270/Q24T6J2X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM50215816 (2-(4-acetylphenylamino)-N,N-diisopentyl-3-(3-(pipe...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Displacement of [125I]NDP-alphaMSH from human melanocortin 1 receptor expressed in CHOK1 cells | Bioorg Med Chem Lett 17: 4464-70 (2007) Article DOI: 10.1016/j.bmcl.2007.06.010 BindingDB Entry DOI: 10.7270/Q24T6J2X | |||||||||||
More data for this Ligand-Target Pair |