Found 8 hits for monomerid = 50215861 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole blood |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
Leukotriene B4 receptor 1/2
(Homo sapiens (Human)) | BDBM50215861
(CHEMBL298724)Show SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cccc(F)c1C(O)=O Show InChI InChI=1S/C23H19FO4/c24-19-8-4-7-17(21(19)23(26)27)15-9-10-18-20(12-15)28-13-16(22(18)25)11-14-5-2-1-3-6-14/h1-10,12,16,22,25H,11,13H2,(H,26,27)/t16-,22+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils. |
Bioorg Med Chem Lett 8: 1781-6 (1998)
BindingDB Entry DOI: 10.7270/Q2RR21F1 |
More data for this
Ligand-Target Pair | |
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