BDBM50215868 CHEMBL51535

SMILES: NS(=O)(=O)c1ccc(F)cc1-c1ccc2[C@H](O)[C@@H](Cc3ccccc3)COc2c1

InChI Key: InChIKey=UUICILBXPJNMBR-KSFYIVLOSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50215868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50215868 (CHEMBL51535) Show SMILES NS(=O)(=O)c1ccc(F)cc1-c1ccc2[C@H](O)[C@@H](Cc3ccccc3)COc2c1 Show InChI InChI=1S/C22H20FNO4S/c23-17-7-9-21(29(24,26)27)19(12-17)15-6-8-18-20(11-15)28-13-16(22(18)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H2,24,26,27)/t16-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils				Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1
					More data for this Ligand-Target Pair
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50215868 (CHEMBL51535) Show SMILES NS(=O)(=O)c1ccc(F)cc1-c1ccc2[C@H](O)[C@@H](Cc3ccccc3)COc2c1 Show InChI InChI=1S/C22H20FNO4S/c23-17-7-9-21(29(24,26)27)19(12-17)15-6-8-18-20(11-15)28-13-16(22(18)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H2,24,26,27)/t16-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.				Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1
					More data for this Ligand-Target Pair
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50215868 (CHEMBL51535) Show SMILES NS(=O)(=O)c1ccc(F)cc1-c1ccc2[C@H](O)[C@@H](Cc3ccccc3)COc2c1 Show InChI InChI=1S/C22H20FNO4S/c23-17-7-9-21(29(24,26)27)19(12-17)15-6-8-18-20(11-15)28-13-16(22(18)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H2,24,26,27)/t16-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole blood				Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1
					More data for this Ligand-Target Pair
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50215868 (CHEMBL51535) Show SMILES NS(=O)(=O)c1ccc(F)cc1-c1ccc2[C@H](O)[C@@H](Cc3ccccc3)COc2c1 Show InChI InChI=1S/C22H20FNO4S/c23-17-7-9-21(29(24,26)27)19(12-17)15-6-8-18-20(11-15)28-13-16(22(18)25)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,25H,10,13H2,(H2,24,26,27)/t16-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.				Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1
					More data for this Ligand-Target Pair