BDBM50215887 CHEMBL130841

SMILES: CCOC(=O)N1CCC(Cc2ccncc2)(C1=O)c1ccc(OC)c(OC2CCCC2)c1

InChI Key: InChIKey=SMJWZBPNUICRQK-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50215887 (CHEMBL130841) Show SMILES CCOC(=O)N1CCC(Cc2ccncc2)(C1=O)c1ccc(OC)c(OC2CCCC2)c1 Show InChI InChI=1S/C25H30N2O5/c1-3-31-24(29)27-15-12-25(23(27)28,17-18-10-13-26-14-11-18)19-8-9-21(30-2)22(16-19)32-20-6-4-5-7-20/h8-11,13-14,16,20H,3-7,12,15,17H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	139	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Affinity for phosphodiesterase (PDE IV) in guinea pig brain membrane using [3H]rolipram displacement.				Bioorg Med Chem Lett 8: 399-404 (1998) BindingDB Entry DOI: 10.7270/Q2222WZ0
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50215887 (CHEMBL130841) Show SMILES CCOC(=O)N1CCC(Cc2ccncc2)(C1=O)c1ccc(OC)c(OC2CCCC2)c1 Show InChI InChI=1S/C25H30N2O5/c1-3-31-24(29)27-15-12-25(23(27)28,17-18-10-13-26-14-11-18)19-8-9-21(30-2)22(16-19)32-20-6-4-5-7-20/h8-11,13-14,16,20H,3-7,12,15,17H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of phosphodiesterase (PDE IV) from guinea pig macrophages.				Bioorg Med Chem Lett 8: 399-404 (1998) BindingDB Entry DOI: 10.7270/Q2222WZ0
					More data for this Ligand-Target Pair