BDBM50215941 CHEMBL300395

SMILES: Cc1cn(Cc2cccc(c2)[N+]([O-])=O)c2cc(ccc12)C(=O)Nc1c(Cl)cncc1Cl

InChI Key: InChIKey=SVLRGVZAGQAOSB-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215941   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50215941 (CHEMBL300395) Show SMILES Cc1cn(Cc2cccc(c2)[N+]([O-])=O)c2cc(ccc12)C(=O)Nc1c(Cl)cncc1Cl Show InChI InChI=1S/C22H16Cl2N4O3/c1-13-11-27(12-14-3-2-4-16(7-14)28(30)31)20-8-15(5-6-17(13)20)22(29)26-21-18(23)9-25-10-19(21)24/h2-11H,12H2,1H3,(H,25,26,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Binding affinity against PDE4 was determined using [3H]- rolipram in guinea pig brain membrane binding assay				Bioorg Med Chem Lett 8: 1867-72 (1998) BindingDB Entry DOI: 10.7270/Q2CJ8GPB
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50215941 (CHEMBL300395) Show SMILES Cc1cn(Cc2cccc(c2)[N+]([O-])=O)c2cc(ccc12)C(=O)Nc1c(Cl)cncc1Cl Show InChI InChI=1S/C22H16Cl2N4O3/c1-13-11-27(12-14-3-2-4-16(7-14)28(30)31)20-8-15(5-6-17(13)20)22(29)26-21-18(23)9-25-10-19(21)24/h2-11H,12H2,1H3,(H,25,26,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Inhibitory activity against Phosphodiesterase type IV (PDE4) obtained from guinea-pig macrophage was evaluated				Bioorg Med Chem Lett 8: 1867-72 (1998) BindingDB Entry DOI: 10.7270/Q2CJ8GPB
					More data for this Ligand-Target Pair