BDBM50215961 CHEMBL128476

SMILES: COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)CCNC1=O

InChI Key: InChIKey=IJZDPIQKKPPCEB-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50215961 (CHEMBL128476) Show SMILES COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)CCNC1=O Show InChI InChI=1S/C22H26N2O3/c1-26-19-7-6-17(14-20(19)27-18-4-2-3-5-18)22(10-13-24-21(22)25)15-16-8-11-23-12-9-16/h6-9,11-12,14,18H,2-5,10,13,15H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Affinity for phosphodiesterase (PDE IV) in guinea pig brain membrane using [3H]rolipram displacement.				Bioorg Med Chem Lett 8: 399-404 (1998) BindingDB Entry DOI: 10.7270/Q2222WZ0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50215961 (CHEMBL128476) Show SMILES COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)CCNC1=O Show InChI InChI=1S/C22H26N2O3/c1-26-19-7-6-17(14-20(19)27-18-4-2-3-5-18)22(10-13-24-21(22)25)15-16-8-11-23-12-9-16/h6-9,11-12,14,18H,2-5,10,13,15H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of phosphodiesterase (PDE IV) from guinea pig macrophages.				Bioorg Med Chem Lett 8: 399-404 (1998) BindingDB Entry DOI: 10.7270/Q2222WZ0
					More data for this Ligand-Target Pair