null
SMILES: COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)CCN(Cc2ccc3ccccc3c2)C1=O
InChI Key: InChIKey=WDIRFWGTTLSFDP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human)) | BDBM50216147 (CHEMBL134237) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description Affinity for phosphodiesterase (PDE IV) in guinea pig brain membrane using [3H]rolipram displacement. | Bioorg Med Chem Lett 8: 399-404 (1998) BindingDB Entry DOI: 10.7270/Q2222WZ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human)) | BDBM50216147 (CHEMBL134237) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description In vitro inhibition of phosphodiesterase (PDE IV) from guinea pig macrophages. | Bioorg Med Chem Lett 8: 399-404 (1998) BindingDB Entry DOI: 10.7270/Q2222WZ0 | |||||||||||
More data for this Ligand-Target Pair |