BDBM50216155 CHEMBL337660

SMILES: COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)CCN(C(=O)OC(C)C)C1=O

InChI Key: InChIKey=FOVVRXVNPNCZHA-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50216155   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50216155 (CHEMBL337660) Show SMILES COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)CCN(C(=O)OC(C)C)C1=O Show InChI InChI=1S/C26H32N2O5/c1-18(2)32-25(30)28-15-12-26(24(28)29,17-19-10-13-27-14-11-19)20-8-9-22(31-3)23(16-20)33-21-6-4-5-7-21/h8-11,13-14,16,18,21H,4-7,12,15,17H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Affinity for phosphodiesterase (PDE IV) in guinea pig brain membrane using [3H]rolipram displacement.				Bioorg Med Chem Lett 8: 399-404 (1998) BindingDB Entry DOI: 10.7270/Q2222WZ0
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50216155 (CHEMBL337660) Show SMILES COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)CCN(C(=O)OC(C)C)C1=O Show InChI InChI=1S/C26H32N2O5/c1-18(2)32-25(30)28-15-12-26(24(28)29,17-19-10-13-27-14-11-19)20-8-9-22(31-3)23(16-20)33-21-6-4-5-7-21/h8-11,13-14,16,18,21H,4-7,12,15,17H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of phosphodiesterase (PDE IV) from guinea pig macrophages.				Bioorg Med Chem Lett 8: 399-404 (1998) BindingDB Entry DOI: 10.7270/Q2222WZ0
					More data for this Ligand-Target Pair