BDBM50216182 CHEMBL232778::N-(2-ethoxyphenethyl)-4-((diethylamino)methyl)-N-(pyrrolidin-3-yl)benzamide

SMILES: CCOc1ccccc1CCN(C1CCNC1)C(=O)c1ccc(CN(CC)CC)cc1

InChI Key: InChIKey=QCKROCAKQPVWRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane-bound transcription factor site-1 protease (Homo sapiens (Human))	BDBM50216182 (CHEMBL232778 | N-(2-ethoxyphenethyl)-4-((diethylam...) Show SMILES CCOc1ccccc1CCN(C1CCNC1)C(=O)c1ccc(CN(CC)CC)cc1 |w:12.12| Show InChI InChI=1S/C26H37N3O2/c1-4-28(5-2)20-21-11-13-23(14-12-21)26(30)29(24-15-17-27-19-24)18-16-22-9-7-8-10-25(22)31-6-3/h7-14,24,27H,4-6,15-20H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-Groton Laboratories Curated by ChEMBL					Assay Description Inhibition of human S1P expressed in CHOK1 cells				Bioorg Med Chem Lett 17: 4411-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.031 BindingDB Entry DOI: 10.7270/Q26M36JG
					More data for this Ligand-Target Pair