BDBM50216185 CHEMBL397866::N-(2-chlorophenethyl)-4-isopropoxy-N-(1-methylpyrrolidin-3-yl)benzamide

SMILES: CC(C)Oc1ccc(cc1)C(=O)N(CCc1ccccc1Cl)C1CCN(C)C1

InChI Key: InChIKey=QBMZTZAXLYSALZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216185   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane-bound transcription factor site-1 protease (Homo sapiens (Human))	BDBM50216185 (CHEMBL397866 | N-(2-chlorophenethyl)-4-isopropoxy-...) Show SMILES CC(C)Oc1ccc(cc1)C(=O)N(CCc1ccccc1Cl)C1CCN(C)C1 |w:22.23| Show InChI InChI=1S/C23H29ClN2O2/c1-17(2)28-21-10-8-19(9-11-21)23(27)26(20-13-14-25(3)16-20)15-12-18-6-4-5-7-22(18)24/h4-11,17,20H,12-16H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-Groton Laboratories Curated by ChEMBL					Assay Description Inhibition of human S1P expressed in CHOK1 cells				Bioorg Med Chem Lett 17: 4411-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.031 BindingDB Entry DOI: 10.7270/Q26M36JG
					More data for this Ligand-Target Pair