BDBM50216187 CHEMBL232777::N-(3-chlorophenethyl)-4-(benzyloxy)-N-(pyrrolidin-3-yl)benzamide

SMILES: Clc1cccc(CCN(C2CCNC2)C(=O)c2ccc(OCc3ccccc3)cc2)c1

InChI Key: InChIKey=DSMOSSPRJOLACS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane-bound transcription factor site-1 protease (Homo sapiens (Human))	BDBM50216187 (CHEMBL232777 | N-(3-chlorophenethyl)-4-(benzyloxy)...) Show SMILES Clc1cccc(CCN(C2CCNC2)C(=O)c2ccc(OCc3ccccc3)cc2)c1 |w:9.8| Show InChI InChI=1S/C26H27ClN2O2/c27-23-8-4-7-20(17-23)14-16-29(24-13-15-28-18-24)26(30)22-9-11-25(12-10-22)31-19-21-5-2-1-3-6-21/h1-12,17,24,28H,13-16,18-19H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-Groton Laboratories Curated by ChEMBL					Assay Description Inhibition of human S1P expressed in CHOK1 cells				Bioorg Med Chem Lett 17: 4411-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.031 BindingDB Entry DOI: 10.7270/Q26M36JG
					More data for this Ligand-Target Pair