BDBM50216190 CHEMBL232776::N-(4-chlorophenethyl)-4-((diethylamino)methyl)-N-(pyrrolidin-3-yl)benzamide

SMILES: CCN(CC)Cc1ccc(cc1)C(=O)N(CCc1ccc(Cl)cc1)C1CCNC1

InChI Key: InChIKey=FUYGSVMPRFVNAM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane-bound transcription factor site-1 protease (Homo sapiens (Human))	BDBM50216190 (CHEMBL232776 | N-(4-chlorophenethyl)-4-((diethylam...) Show SMILES CCN(CC)Cc1ccc(cc1)C(=O)N(CCc1ccc(Cl)cc1)C1CCNC1 |w:24.25| Show InChI InChI=1S/C24H32ClN3O/c1-3-27(4-2)18-20-5-9-21(10-6-20)24(29)28(23-13-15-26-17-23)16-14-19-7-11-22(25)12-8-19/h5-12,23,26H,3-4,13-18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-Groton Laboratories Curated by ChEMBL					Assay Description Inhibition of human S1P expressed in CHOK1 cells				Bioorg Med Chem Lett 17: 4411-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.031 BindingDB Entry DOI: 10.7270/Q26M36JG
					More data for this Ligand-Target Pair