BDBM50216198 CHEMBL233419::N-(2-chlorophenethyl)-4-isopropoxy-N-(tetrahydrothiophen-3-yl)benzamide

SMILES: CC(C)Oc1ccc(cc1)C(=O)N(CCc1ccccc1Cl)C1CCSC1

InChI Key: InChIKey=YUPRJOJXEFMKBX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane-bound transcription factor site-1 protease (Homo sapiens (Human))	BDBM50216198 (CHEMBL233419 | N-(2-chlorophenethyl)-4-isopropoxy-...) Show SMILES CC(C)Oc1ccc(cc1)C(=O)N(CCc1ccccc1Cl)C1CCSC1 |w:22.23| Show InChI InChI=1S/C22H26ClNO2S/c1-16(2)26-20-9-7-18(8-10-20)22(25)24(19-12-14-27-15-19)13-11-17-5-3-4-6-21(17)23/h3-10,16,19H,11-15H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-Groton Laboratories Curated by ChEMBL					Assay Description Inhibition of human S1P expressed in CHOK1 cells				Bioorg Med Chem Lett 17: 4411-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.031 BindingDB Entry DOI: 10.7270/Q26M36JG
					More data for this Ligand-Target Pair