BDBM50216201 CHEMBL233987::N-(2-methoxyphenethyl)-4-(6-aza-bicyclo[3.2.1]octan-6-ylmethyl)-N-(pyrrolidin-3-yl)benzamide

SMILES: COc1ccccc1CCN(C1CCNC1)C(=O)c1ccc(CN2CC3CC2CCC3)cc1

InChI Key: InChIKey=QAPWXKPJZPOITM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane-bound transcription factor site-1 protease (Homo sapiens (Human))	BDBM50216201 (CHEMBL233987 | N-(2-methoxyphenethyl)-4-(6-aza-bic...) Show SMILES COc1ccccc1CCN(C1CCNC1)C(=O)c1ccc(CN2CC3CC2CCC3)cc1 |w:11.11,25.27,27.30,THB:22:23:26:30.29.28| Show InChI InChI=1S/C28H37N3O2/c1-33-27-8-3-2-6-23(27)14-16-31(26-13-15-29-18-26)28(32)24-11-9-21(10-12-24)19-30-20-22-5-4-7-25(30)17-22/h2-3,6,8-12,22,25-26,29H,4-5,7,13-20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-Groton Laboratories Curated by ChEMBL					Assay Description Inhibition of human S1P expressed in CHOK1 cells				Bioorg Med Chem Lett 17: 4411-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.031 BindingDB Entry DOI: 10.7270/Q26M36JG
					More data for this Ligand-Target Pair