BDBM50216203 4-diethylaminomethyl-N-pyrrolidin-3-yl-N-(2-o-tolyl-ethyl)-benzamide::CHEMBL393377

SMILES: CCN(CC)Cc1ccc(cc1)C(=O)N(CCc1ccccc1C)C1CCNC1

InChI Key: InChIKey=DGLGFXRWXZRMHG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane-bound transcription factor site-1 protease (Homo sapiens (Human))	BDBM50216203 (4-diethylaminomethyl-N-pyrrolidin-3-yl-N-(2-o-toly...) Show SMILES CCN(CC)Cc1ccc(cc1)C(=O)N(CCc1ccccc1C)C1CCNC1 |w:24.25| Show InChI InChI=1S/C25H35N3O/c1-4-27(5-2)19-21-10-12-23(13-11-21)25(29)28(24-14-16-26-18-24)17-15-22-9-7-6-8-20(22)3/h6-13,24,26H,4-5,14-19H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-Groton Laboratories Curated by ChEMBL					Assay Description Inhibition of human S1P expressed in CHOK1 cells				Bioorg Med Chem Lett 17: 4411-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.031 BindingDB Entry DOI: 10.7270/Q26M36JG
					More data for this Ligand-Target Pair