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SMILES: COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)C(=O)Nc2ccccc12

InChI Key: InChIKey=LYFJUEFLHDDPGU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50216308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50216308 (CHEMBL297296) Show SMILES COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)C(=O)Nc2ccccc12 Show InChI InChI=1S/C26H26N2O3/c1-30-23-11-10-19(16-24(23)31-20-6-2-3-7-20)26(17-18-12-14-27-15-13-18)21-8-4-5-9-22(21)28-25(26)29/h4-5,8-16,20H,2-3,6-7,17H2,1H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Displacement of [3H]rolipram binding to guinea pig brain membrane				Bioorg Med Chem Lett 8: 175-8 (1998) BindingDB Entry DOI: 10.7270/Q26T0PTS
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50216308 (CHEMBL297296) Show SMILES COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)C(=O)Nc2ccccc12 Show InChI InChI=1S/C26H26N2O3/c1-30-23-11-10-19(16-24(23)31-20-6-2-3-7-20)26(17-18-12-14-27-15-13-18)21-8-4-5-9-22(21)28-25(26)29/h4-5,8-16,20H,2-3,6-7,17H2,1H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Central Research Curated by ChEMBL					Assay Description Inhibition of guinea pig macrophage Phosphodiesterase 4				Bioorg Med Chem Lett 8: 175-8 (1998) BindingDB Entry DOI: 10.7270/Q26T0PTS
					More data for this Ligand-Target Pair