BDBM50216488 5-(2-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione::CHEMBL398171

SMILES: Clc1ccccc1Cc1c([nH]c(=O)[nH]c1=O)N1CCC(CC1)c1ccccc1

InChI Key: InChIKey=ZBJXBIMZENDRKV-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50216488   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50216488 (5-(2-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...) Show SMILES Clc1ccccc1Cc1c([nH]c(=O)[nH]c1=O)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C22H22ClN3O2/c23-19-9-5-4-8-17(19)14-18-20(24-22(28)25-21(18)27)26-12-10-16(11-13-26)15-6-2-1-3-7-15/h1-9,16H,10-14H2,(H2,24,25,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 17: 4901-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.036 BindingDB Entry DOI: 10.7270/Q21Z444J
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50216488 (5-(2-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...) Show SMILES Clc1ccccc1Cc1c([nH]c(=O)[nH]c1=O)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C22H22ClN3O2/c23-19-9-5-4-8-17(19)14-18-20(24-22(28)25-21(18)27)26-12-10-16(11-13-26)15-6-2-1-3-7-15/h1-9,16H,10-14H2,(H2,24,25,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd Curated by ChEMBL					Assay Description Antagonist activity at human GR				Bioorg Med Chem Lett 17: 4901-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.036 BindingDB Entry DOI: 10.7270/Q21Z444J
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50216488 (5-(2-chlorobenzyl)-6-(4-phenylpiperidin-1-yl)pyrim...) Show SMILES Clc1ccccc1Cc1c([nH]c(=O)[nH]c1=O)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C22H22ClN3O2/c23-19-9-5-4-8-17(19)14-18-20(24-22(28)25-21(18)27)26-12-10-16(11-13-26)15-6-2-1-3-7-15/h1-9,16H,10-14H2,(H2,24,25,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from mineralocorticoid receptor expressed in Sf9 cells				Bioorg Med Chem Lett 17: 4901-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.036 BindingDB Entry DOI: 10.7270/Q21Z444J
					More data for this Ligand-Target Pair