BDBM50216551 3-pentyl-1H-pyrazole-5-carboxylic acid::5-butylpyrazole-3-carboxylic acid::5-pentyl-1H-pyrazole-3-carboxylic acid::CHEMBL247921

SMILES: CCCCCc1cc(n[nH]1)C(O)=O

InChI Key: InChIKey=ZHDMNUKZNCXRJD-UHFFFAOYSA-N

Data: 1 KI  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50216551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50216551 (3-pentyl-1H-pyrazole-5-carboxylic acid | 5-butylpy...) Show SMILES CCCCCc1cc(n[nH]1)C(O)=O Show InChI InChI=1S/C9H14N2O2/c1-2-3-4-5-7-6-8(9(12)13)11-10-7/h6H,2-5H2,1H3,(H,10,11)(H,12,13)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity at GPR109a				J Med Chem 51: 7653-62 (2008) Article DOI: 10.1021/jm800896z BindingDB Entry DOI: 10.7270/Q27D2TZ5
					More data for this Ligand-Target Pair
HM74 nicotinic acid GPCR (Homo sapiens (Human))	BDBM50216551 (3-pentyl-1H-pyrazole-5-carboxylic acid | 5-butylpy...) Show SMILES CCCCCc1cc(n[nH]1)C(O)=O Show InChI InChI=1S/C9H14N2O2/c1-2-3-4-5-7-6-8(9(12)13)11-10-7/h6H,2-5H2,1H3,(H,10,11)(H,12,13)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay				Bioorg Med Chem Lett 17: 5620-3 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.07.101 BindingDB Entry DOI: 10.7270/Q2TT4QN2
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50216551 (3-pentyl-1H-pyrazole-5-carboxylic acid | 5-butylpy...) Show SMILES CCCCCc1cc(n[nH]1)C(O)=O Show InChI InChI=1S/C9H14N2O2/c1-2-3-4-5-7-6-8(9(12)13)11-10-7/h6H,2-5H2,1H3,(H,10,11)(H,12,13)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test				Bioorg Med Chem Lett 17: 4914-9 (2007) Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50216551 (3-pentyl-1H-pyrazole-5-carboxylic acid | 5-butylpy...) Show SMILES CCCCCc1cc(n[nH]1)C(O)=O Show InChI InChI=1S/C9H14N2O2/c1-2-3-4-5-7-6-8(9(12)13)11-10-7/h6H,2-5H2,1H3,(H,10,11)(H,12,13)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay				Bioorg Med Chem Lett 17: 5620-3 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.07.101 BindingDB Entry DOI: 10.7270/Q2TT4QN2
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50216551 (3-pentyl-1H-pyrazole-5-carboxylic acid | 5-butylpy...) Show SMILES CCCCCc1cc(n[nH]1)C(O)=O Show InChI InChI=1S/C9H14N2O2/c1-2-3-4-5-7-6-8(9(12)13)11-10-7/h6H,2-5H2,1H3,(H,10,11)(H,12,13)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay				Bioorg Med Chem Lett 17: 5620-3 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.07.101 BindingDB Entry DOI: 10.7270/Q2TT4QN2
					More data for this Ligand-Target Pair