BindingDB PrimarySearch

BDBM50216557 5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benzamido)cyclopentyl)thiophene-2-carboxamide::CHEMBL399593

SMILES: Clc1ccc(s1)C(=O)N[C@@H]1CCC[C@@H]1NC(=O)c1ccc(cc1)N1CCCCC1=O

InChI Key: InChIKey=FIUKRBJFYYATCX-DLBZAZTESA-N

Data: 8 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50216557
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50216557 (5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 4419-27 (2007) Article DOI: 10.1016/j.bmcl.2007.06.029 BindingDB Entry DOI: 10.7270/Q2416XVV
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50216557 (5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human thrombin				Bioorg Med Chem Lett 17: 4419-27 (2007) Article DOI: 10.1016/j.bmcl.2007.06.029 BindingDB Entry DOI: 10.7270/Q2416XVV
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM50216557 (5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human plasma kallikrein				Bioorg Med Chem Lett 17: 4419-27 (2007) Article DOI: 10.1016/j.bmcl.2007.06.029 BindingDB Entry DOI: 10.7270/Q2416XVV
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50216557 (5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 7a				Bioorg Med Chem Lett 17: 4419-27 (2007) Article DOI: 10.1016/j.bmcl.2007.06.029 BindingDB Entry DOI: 10.7270/Q2416XVV
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM50216557 (5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 11a				Bioorg Med Chem Lett 17: 4419-27 (2007) Article DOI: 10.1016/j.bmcl.2007.06.029 BindingDB Entry DOI: 10.7270/Q2416XVV
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50216557 (5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human urokinase				Bioorg Med Chem Lett 17: 4419-27 (2007) Article DOI: 10.1016/j.bmcl.2007.06.029 BindingDB Entry DOI: 10.7270/Q2416XVV
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50216557 (5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human tPA				Bioorg Med Chem Lett 17: 4419-27 (2007) Article DOI: 10.1016/j.bmcl.2007.06.029 BindingDB Entry DOI: 10.7270/Q2416XVV
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50216557 (5-chloro-N-((1R,2S)-2-(4-(2-oxopiperidin-1-yl)benz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human plasmin				Bioorg Med Chem Lett 17: 4419-27 (2007) Article DOI: 10.1016/j.bmcl.2007.06.029 BindingDB Entry DOI: 10.7270/Q2416XVV
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair