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BDBM50216566 5-chloro-N-((1R,2S)-2-(4-(2-oxopyrazin-1(2H)-yl)benzamido)cyclopentyl)thiophene-2-carboxamide::CHEMBL233543

SMILES: Clc1ccc(s1)C(=O)N[C@@H]1CCC[C@@H]1NC(=O)c1ccc(cc1)-n1ccncc1=O

InChI Key: InChIKey=LGQYJYMAFFOQCV-JKSUJKDBSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216566   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50216566
PNG
(5-chloro-N-((1R,2S)-2-(4-(2-oxopyrazin-1(2H)-yl)be...)
Show SMILES Clc1ccc(s1)C(=O)N[C@@H]1CCC[C@@H]1NC(=O)c1ccc(cc1)-n1ccncc1=O
Show InChI InChI=1S/C21H19ClN4O3S/c22-18-9-8-17(30-18)21(29)25-16-3-1-2-15(16)24-20(28)13-4-6-14(7-5-13)26-11-10-23-12-19(26)27/h4-12,15-16H,1-3H2,(H,24,28)(H,25,29)/t15-,16+/m0/s1
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Article
PubMed
1.10n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 4419-27 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.029
BindingDB Entry DOI: 10.7270/Q2416XVV
More data for this
Ligand-Target Pair