BDBM50216568 3-chloro-1H-indole-6-carboxylic acid {(1R,2S)-2-[4-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-benzoylamino]-cyclohexyl}-amide::CHEMBL234171

SMILES: Clc1c[nH]c2cc(ccc12)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)c1ccc(cc1)N1CCCS1(=O)=O

InChI Key: InChIKey=BQZPBHUHBATTHG-FCHUYYIVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50216568 (3-chloro-1H-indole-6-carboxylic acid {(1R,2S)-2-[4...) Show SMILES Clc1c[nH]c2cc(ccc12)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)c1ccc(cc1)N1CCCS1(=O)=O Show InChI InChI=1S/C25H27ClN4O4S/c26-20-15-27-23-14-17(8-11-19(20)23)25(32)29-22-5-2-1-4-21(22)28-24(31)16-6-9-18(10-7-16)30-12-3-13-35(30,33)34/h6-11,14-15,21-22,27H,1-5,12-13H2,(H,28,31)(H,29,32)/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 4419-27 (2007) Article DOI: 10.1016/j.bmcl.2007.06.029 BindingDB Entry DOI: 10.7270/Q2416XVV
					More data for this Ligand-Target Pair