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BDBM50216584 3-chloro-N-((1R,2S)-2-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)benzamido)cyclohexyl)-1H-indole-6-carboxamide::CHEMBL400227

SMILES: Clc1c[nH]c2cc(ccc12)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)c1ccc(cc1)C1(CN2CCCC2)CC1

InChI Key: InChIKey=NVXXNOPBCMKLSI-IZZNHLLZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216584   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50216584
PNG
(3-chloro-N-((1R,2S)-2-(4-(1-(pyrrolidin-1-ylmethyl...)
Show SMILES Clc1c[nH]c2cc(ccc12)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)c1ccc(cc1)C1(CN2CCCC2)CC1
Show InChI InChI=1S/C30H35ClN4O2/c31-24-18-32-27-17-21(9-12-23(24)27)29(37)34-26-6-2-1-5-25(26)33-28(36)20-7-10-22(11-8-20)30(13-14-30)19-35-15-3-4-16-35/h7-12,17-18,25-26,32H,1-6,13-16,19H2,(H,33,36)(H,34,37)/t25-,26+/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
0.440n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 4419-27 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.029
BindingDB Entry DOI: 10.7270/Q2416XVV
More data for this
Ligand-Target Pair