BDBM50216586 CHEMBL233173::cis-N-(2-(4-(2-oxopyridin-1(2H)-yl)benzylamino)cyclopentyl)-5-chlorothiophene-2-carboxamide

SMILES: Clc1ccc(s1)C(=O)N[C@@H]1CCC[C@@H]1NCc1ccc(cc1)-n1ccccc1=O

InChI Key: InChIKey=FXPCHMPXRVUXGJ-ZWKOTPCHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50216586 (CHEMBL233173 | cis-N-(2-(4-(2-oxopyridin-1(2H)-yl)...) Show SMILES Clc1ccc(s1)C(=O)N[C@@H]1CCC[C@@H]1NCc1ccc(cc1)-n1ccccc1=O Show InChI InChI=1S/C22H22ClN3O2S/c23-20-12-11-19(29-20)22(28)25-18-5-3-4-17(18)24-14-15-7-9-16(10-8-15)26-13-2-1-6-21(26)27/h1-2,6-13,17-18,24H,3-5,14H2,(H,25,28)/t17-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 4419-27 (2007) Article DOI: 10.1016/j.bmcl.2007.06.029 BindingDB Entry DOI: 10.7270/Q2416XVV
					More data for this Ligand-Target Pair