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BDBM50216606 3-chloro-N-(2-methyl-1-(4-(2-oxopyridin-1(2H)-yl)benzamido)propan-2-yl)-1H-indole-6-carboxamide::CHEMBL393815

SMILES: CC(C)(CNC(=O)c1ccc(cc1)-n1ccccc1=O)NC(=O)c1ccc2c(Cl)c[nH]c2c1

InChI Key: InChIKey=PCIFBPUEOJKFOX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50216606
PNG
(3-chloro-N-(2-methyl-1-(4-(2-oxopyridin-1(2H)-yl)b...)
Show SMILES CC(C)(CNC(=O)c1ccc(cc1)-n1ccccc1=O)NC(=O)c1ccc2c(Cl)c[nH]c2c1
Show InChI InChI=1S/C25H23ClN4O3/c1-25(2,29-24(33)17-8-11-19-20(26)14-27-21(19)13-17)15-28-23(32)16-6-9-18(10-7-16)30-12-4-3-5-22(30)31/h3-14,27H,15H2,1-2H3,(H,28,32)(H,29,33)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
1.30n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 4419-27 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.029
BindingDB Entry DOI: 10.7270/Q2416XVV
More data for this
Ligand-Target Pair