BDBM50216683 1-(5-iodonaphthalen-1-ylsulfonyl)-1,4-diazepane::CHEMBL249089
SMILES: Ic1cccc2c(cccc12)S(=O)(=O)N1CCCNCC1
InChI Key: InChIKey=GEHJIACZUFWBTK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Myosin light chain kinase, smooth muscle (Homo sapiens (Human)) | BDBM50216683 (1-(5-iodonaphthalen-1-ylsulfonyl)-1,4-diazepane | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Genomics Centre of the Max Planck Society Curated by ChEMBL | Assay Description Inhibition of MLCK by HTRF assay | Bioorg Med Chem 19: 429-39 (2011) Article DOI: 10.1016/j.bmc.2010.11.007 BindingDB Entry DOI: 10.7270/Q22F7NQN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase Pfmrk (Plasmodium falciparum) | BDBM50216683 (1-(5-iodonaphthalen-1-ylsulfonyl)-1,4-diazepane | ...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum Pfmrk | Bioorg Med Chem Lett 17: 4961-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.032 BindingDB Entry DOI: 10.7270/Q2GX4CC8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50216683 (1-(5-iodonaphthalen-1-ylsulfonyl)-1,4-diazepane | ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kalypsys, Inc. Curated by ChEMBL | Assay Description Inhibition of ROCK1 assessed as ATP cunsumption | Bioorg Med Chem Lett 20: 3361-6 (2010) Article DOI: 10.1016/j.bmcl.2010.04.020 BindingDB Entry DOI: 10.7270/Q289161H | |||||||||||
More data for this Ligand-Target Pair |