BDBM50216749 3-(methoxymethyl)-5-(2-methylquinolin-7-yl)benzonitrile::CHEMBL231790

SMILES: COCc1cc(cc(c1)-c1ccc2ccc(C)nc2c1)C#N

InChI Key: InChIKey=VODJFWOLGVBSJY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50216749 (3-(methoxymethyl)-5-(2-methylquinolin-7-yl)benzoni...) Show SMILES COCc1cc(cc(c1)-c1ccc2ccc(C)nc2c1)C#N Show InChI InChI=1S/C19H16N2O/c1-13-3-4-16-5-6-17(10-19(16)21-13)18-8-14(11-20)7-15(9-18)12-22-2/h3-10H,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 17: 4415-8 (2007) Article DOI: 10.1016/j.bmcl.2007.06.030 BindingDB Entry DOI: 10.7270/Q28G8KDC
					More data for this Ligand-Target Pair