BDBM50216887 1-((1H-benzo[d]imidazol-2-yl)methyl)-3-(5-methoxybenzo[d]thiazol-2-yl)urea::CHEMBL237637

SMILES: COc1ccc2sc(NC(=O)NCc3nc4ccccc4[nH]3)nc2c1

InChI Key: InChIKey=TYBRGTOCRZCDLR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50216887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-ACP Reductase (FabK) (Streptococcus pneumoniae)	BDBM50216887 (1-((1H-benzo[d]imidazol-2-yl)methyl)-3-(5-methoxyb...) Show SMILES COc1ccc2sc(NC(=O)NCc3nc4ccccc4[nH]3)nc2c1 Show InChI InChI=1S/C17H15N5O2S/c1-24-10-6-7-14-13(8-10)21-17(25-14)22-16(23)18-9-15-19-11-4-2-3-5-12(11)20-15/h2-8H,9H2,1H3,(H,19,20)(H2,18,21,22,23)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha Ltd Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae KU197 FabK				Bioorg Med Chem Lett 17: 4982-6 (2007) Article DOI: 10.1016/j.bmcl.2007.06.040 BindingDB Entry DOI: 10.7270/Q2C53MP9
					More data for this Ligand-Target Pair
Enoyl-ACP Reductase (FabK) (Streptococcus pneumoniae)	BDBM50216887 (1-((1H-benzo[d]imidazol-2-yl)methyl)-3-(5-methoxyb...) Show SMILES COc1ccc2sc(NC(=O)NCc3nc4ccccc4[nH]3)nc2c1 Show InChI InChI=1S/C17H15N5O2S/c1-24-10-6-7-14-13(8-10)21-17(25-14)22-16(23)18-9-15-19-11-4-2-3-5-12(11)20-15/h2-8H,9H2,1H3,(H,19,20)(H2,18,21,22,23)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae enoyl-ACP reductase FabK				Bioorg Med Chem 15: 7325-36 (2007) Article DOI: 10.1016/j.bmc.2007.08.050 BindingDB Entry DOI: 10.7270/Q25T3MBH
					More data for this Ligand-Target Pair
Enoyl-ACP Reductase (FabI) (Escherichia coli)	BDBM50216887 (1-((1H-benzo[d]imidazol-2-yl)methyl)-3-(5-methoxyb...) Show SMILES COc1ccc2sc(NC(=O)NCc3nc4ccccc4[nH]3)nc2c1 Show InChI InChI=1S/C17H15N5O2S/c1-24-10-6-7-14-13(8-10)21-17(25-14)22-16(23)18-9-15-19-11-4-2-3-5-12(11)20-15/h2-8H,9H2,1H3,(H,19,20)(H2,18,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Meiji Seika Kaisha, Ltd Curated by ChEMBL					Assay Description Inhibition of Escherichia coli enoyl-ACP reductase FabI				Bioorg Med Chem 15: 7325-36 (2007) Article DOI: 10.1016/j.bmc.2007.08.050 BindingDB Entry DOI: 10.7270/Q25T3MBH
					More data for this Ligand-Target Pair