BDBM50217060 1-((1S,2S,5S)-5-(2-(aminomethyl)thiazol-5-yl)bicyclo[3.1.0]hexan-2-yl)-3-(2,6-dichloropyridin-4-yl)-1-(3-((2R,5S)-2,5-dimethylpiperazin-1-yl)propyl)urea::CHEMBL391496

SMILES: C[C@H]1CN(CCCN([C@H]2CC[C@@]3(C[C@H]23)c2cnc(CN)s2)C(=O)Nc2cc(Cl)nc(Cl)c2)[C@H](C)CN1

InChI Key: InChIKey=ZMZHZCSLQGDVJZ-MRILWLIUSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50217060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50217060 (1-((1S,2S,5S)-5-(2-(aminomethyl)thiazol-5-yl)bicyc...) Show SMILES C[C@H]1CN(CCCN([C@H]2CC[C@@]3(C[C@H]23)c2cnc(CN)s2)C(=O)Nc2cc(Cl)nc(Cl)c2)[C@H](C)CN1 Show InChI InChI=1S/C25H35Cl2N7OS/c1-15-14-33(16(2)12-29-15)6-3-7-34(24(35)31-17-8-21(26)32-22(27)9-17)19-4-5-25(10-18(19)25)20-13-30-23(11-28)36-20/h8-9,13,15-16,18-19,29H,3-7,10-12,14,28H2,1-2H3,(H,31,32,35)/t15-,16+,18+,19-,25-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Antagonist activity at MCHR1				Bioorg Med Chem Lett 17: 4845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.06.048 BindingDB Entry DOI: 10.7270/Q2V69J9H
					More data for this Ligand-Target Pair