BDBM50217359 4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)-N-(4-(piperidin-1-yl)phenyl)piperazine-1-carboxamide::CHEMBL234985

SMILES: CO\N=C\c1c(N)ncnc1N1CCN(CC1)C(=O)Nc1ccc(cc1)N1CCCCC1

InChI Key: InChIKey=VGPYFLOGOCAANA-CVKSISIWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50217359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50217359 (4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...) Show SMILES CO\N=C\c1c(N)ncnc1N1CCN(CC1)C(=O)Nc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C22H30N8O2/c1-32-26-15-19-20(23)24-16-25-21(19)29-11-13-30(14-12-29)22(31)27-17-5-7-18(8-6-17)28-9-3-2-4-10-28/h5-8,15-16H,2-4,9-14H2,1H3,(H,27,31)(H2,23,24,25)/b26-15+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Inhibition of human FLT3				Bioorg Med Chem Lett 17: 4861-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.046 BindingDB Entry DOI: 10.7270/Q2T72H47
					More data for this Ligand-Target Pair