BDBM50217361 4-(6-amino-5-((ethoxyimino)methyl)pyrimidin-4-yl)-N-(4-(piperidin-1-yl)phenyl)piperazine-1-carboxamide::CHEMBL428380

SMILES: CCO\N=C\c1c(N)ncnc1N1CCN(CC1)C(=O)Nc1ccc(cc1)N1CCCCC1

InChI Key: InChIKey=CACKYMFTFHFDNM-JVWAILMASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50217361   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50217361 (4-(6-amino-5-((ethoxyimino)methyl)pyrimidin-4-yl)-...) Show SMILES CCO\N=C\c1c(N)ncnc1N1CCN(CC1)C(=O)Nc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C23H32N8O2/c1-2-33-27-16-20-21(24)25-17-26-22(20)30-12-14-31(15-13-30)23(32)28-18-6-8-19(9-7-18)29-10-4-3-5-11-29/h6-9,16-17H,2-5,10-15H2,1H3,(H,28,32)(H2,24,25,26)/b27-16+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Inhibition of human FLT3				Bioorg Med Chem Lett 17: 4861-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.046 BindingDB Entry DOI: 10.7270/Q2T72H47
					More data for this Ligand-Target Pair