BDBM50217362 4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)-N-(6-(cyclopentyloxy)pyridin-3-yl)piperazine-1-carboxamide::CHEMBL238223

SMILES: CO\N=C\c1c(N)ncnc1N1CCN(CC1)C(=O)Nc1ccc(OC2CCCC2)nc1

InChI Key: InChIKey=UEUQYUAIKOMOOP-LGJNPRDNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50217362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50217362 (4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...) Show SMILES CO\N=C\c1c(N)ncnc1N1CCN(CC1)C(=O)Nc1ccc(OC2CCCC2)nc1 Show InChI InChI=1S/C21H28N8O3/c1-31-26-13-17-19(22)24-14-25-20(17)28-8-10-29(11-9-28)21(30)27-15-6-7-18(23-12-15)32-16-4-2-3-5-16/h6-7,12-14,16H,2-5,8-11H2,1H3,(H,27,30)(H2,22,24,25)/b26-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Inhibition of human FLT3				Bioorg Med Chem Lett 17: 4861-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.046 BindingDB Entry DOI: 10.7270/Q2T72H47
					More data for this Ligand-Target Pair