BDBM50217372 3-(4-methoxyphenyl)-N-phenyl-5-(1H-pyrrol-2-yl)-4,5-dihydropyrazole-1-carbothioamide::CHEMBL439556
SMILES: COc1ccc(cc1)C1=NN(C(C1)c1ccc[nH]1)C(=S)Nc1ccccc1
InChI Key: InChIKey=PYGUTGPRQBDIHV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat)) | BDBM50217372 (3-(4-methoxyphenyl)-N-phenyl-5-(1H-pyrrol-2-yl)-4,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University Curated by ChEMBL | Assay Description Inhibition of rat liver MAOB | Bioorg Med Chem 15: 5775-86 (2007) Article DOI: 10.1016/j.bmc.2007.06.004 BindingDB Entry DOI: 10.7270/Q2JH3N0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat)) | BDBM50217372 (3-(4-methoxyphenyl)-N-phenyl-5-(1H-pyrrol-2-yl)-4,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University Curated by ChEMBL | Assay Description Inhibition of rat liver MAOB after 60 mins pre-incubation | Bioorg Med Chem 15: 5775-86 (2007) Article DOI: 10.1016/j.bmc.2007.06.004 BindingDB Entry DOI: 10.7270/Q2JH3N0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoamine oxidase (Rattus norvegicus (rat)) | BDBM50217372 (3-(4-methoxyphenyl)-N-phenyl-5-(1H-pyrrol-2-yl)-4,...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hacettepe University Curated by ChEMBL | Assay Description Inhibition of rat liver MAOA after 60 mins pre-incubation | Bioorg Med Chem 15: 5775-86 (2007) Article DOI: 10.1016/j.bmc.2007.06.004 BindingDB Entry DOI: 10.7270/Q2JH3N0R | |||||||||||
More data for this Ligand-Target Pair |